Genesis 21:11
Isaac is Born
Genesis 21:11

And the thing was very grievous in Abraham's sight because of his son.
Adjacent Verses
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Genesis 21:10
Wherefore she said unto Abraham, Cast out this bondwoman and her son: for the son of this bondwoman shall not be heir with my son, even with Isaac.
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Genesis 21:12
And God said unto Abraham, Let it not be grievous in thy sight because of the lad, and because of thy bondwoman; in all that Sarah hath said unto thee, hearken unto her voice; for in Isaac shall thy seed be called.