The Acts of the Apostles 16:6

The Third Missionary Journey of Paul

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Now when they had gone throughout Phrygia and the region of Galatia, and were forbidden of the Holy Ghost to preach the word in Asia,

And so were the churches established in the faith, and increased in number daily.

After they were come to Mysia, they assayed to go into Bithynia: but the Spirit suffered them not.